A new hydrogel membrane technology that enables you to optimize your downstream processes
As the biopharmaceutical industry shifts to a "flexible facility" manufacturing model, the limits of currently available downstream technologies combined with increased upstream performance has lead to a significant bottleneck in the processing of biopharmaceutical products. This is neither time nor cost effective. Advancements in downstream technology such as depth flow filtration have reduced this over time, however there is as yet no conclusive solution. A recently introduced platform of chromatography products will remove major barriers in this space and enable the shift to truly flexible manufacturing.
These products are based on Natrix HD membrane technology, which utilizes a 3D macro porous hydrogel that is completely functionalized and is capable of high capacity, high selectivity performance, and extremely high flow rates with fast binding kinetics, all in a disposable format.
The device design is optimized according to its mode of action: flowthrough (negative) or bind-elute (positive). These hydrogel membranes outperform current technologies like classical membrane adsorbers, resins and monoliths based on their binding capacity, operational flexibility and easy scalability.
This webinar will review the latest progress with Natrix chromatography tools, including results from case studies with binding mode cation exchange chromatography and flow through mode anion exchange chromatography.
Presented by
Marty Siwak,
Director Separations Sciences Group
Marty Siwak is currently director of the Separations Sciences Group at JSR Life Science Division working from Sunnyvale, California. This team is responsible for process development of purification and separation technologies for the global biopharmaceutical industry. Mr. Siwak has been involved in applied separations and protein purification technology research and development for the past 35 years. He has collaborated with many biotechnology and pharmaceutical companies implementing industrial scale separation technology and holds multiple patents on protein purification technologies. He has BS degrees in both Chemical Engineering and Biochemistry from the University of Connecticut.
Natrix Separations is a leading supplier of high performance, single use and multi-cycle disposable chromatography products to the life science markets. Natrix has developed a unique technology that combines the high binding capacity, selectivity and specificity normally associated with resin-based chromatography with the high throughput and ease of use of traditional membrane products.
The Corporate headquarters are located in Burlington Ontario, which houses administration, research, development, applications, engineering and manufacturing operations.
www.natrixseparations.com
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Key Learning Objectives
- Insight in the mode of action of a new hydrogel membrane technology for downstream processing
- Learn more on the benefits and features of Natrix hydrogel membranes
- How to improve your purification processes for biologics
- Understand the benefits of single use/batch bioprocess devices
Audience
- Head of Process Development
- Scientist DSP
- Group Leaders
- Purification Team Leader
- Director Manufacturing
- Lab Heads
- DSP
- Technology Manager
- Innovation Manager
- Process Development Manager/Scientist/Engineer
